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| MOQ | 1 kg |
| Port | any port |
| Packaging | 25kg/drum |
| Standards | USP | DMF | Yes |
| GMP | Yes |
https://octagonchem.com/products/apis/cyclosporine/
GMP/FDA: Approved
Standards: USP/EP/CP
Sample For Quality Approval: Available
Docs For MOH registration: Available
MOQ: 1KG (Subject To Negotiation)
Lead time: prompt shipment
Cyclosporine, also known as cyclosporin, cyclosporin a or cyclosporine a, is s a white to off-white crystalline solid. It is one of our GMP Approved APIs.
It is an immunosuppressant peptide with eleven amino acids. Other people also call it ciclosporine, cyclosporin, and cyclosporin A, they are the same product. Cyclosporine is mainly used in patients for organ transplants. Cyclosporine can reduce the activity of the patient’s immune system, so it can lower the risks of organ rejection. Cyclosporine can also be used to treat rheumatoid arthritis, psoriasis, Crohn’s disease, nephrotic syndrome. People also make cyclosporine into eye drops for dry eyes.
Cyclosporine and Tacrolimus are two common drugs used for patients of transplantation to achieve adequate immunosuppression and to prevent acute rejection. But what are the differences between cyclosporine and tacrolimus?
Cyclosporine was discovered in 1971 and approved as immunosuppressant drugs for organ transplant rejection. Tacrolimus was not discovered till 1980s and not approved as drug for transplant rejections untill 1989.
Studies conducted by Nephrology Department, Hospital de Santo António, Porto, Portugal has shown that Tacrolimus is less nephrotoxic than cyclosporine. While tacrolimus showed easier blood pressure control but a higher chance to cause diabetes.
Studies have showed that tacrolimus is superior to cyclosporine in terms of survival, graft loss, acute rejection, and steroid-resistant rejection in the first year. Tacrolimus is the most popular for maintenance immunosuppression after liver transplantation.
For pharm-grade cyclosporine and tacrolimus approved by Chinese SFDA, the tacrolimus price is much higher than cyclosporine cost. The tacrolimus price of 100G is about 130usd/g, while the cyclosporine price is about 2500~3000usd/kg. One is sold by GRAM, one is sold by KG. Cyclosporine a is much cheaper than tacrolimus.
Cyclosporine is an organic compound. It is a cyclic peptide with eleven amino acids.
Though cyclosporine is used as an immunosuppressant, it is classified as one group of chemical compounds called other antibiotics with HS code as 2941909090 in China.
For commericial order quantities with GMP&FDA approval, our cyclosporine a price is about1600usd/kg as cnf by air.
For small order quantities of 1kg, our cyclosporine cost is about 2500usd/kg as door-to-door price by express.
We have cyclosporine a for sale till end of March 2020, contact us for a quick order.
If you need cyclosporine for making cyclosporine capsules or cyclosporine tablets, we have cyclosporine GMP and DMF for your moh registration.
If you need cyclosporine for research, check cyclosporine prices from famous reagent companies below. The best price for cyclosporine is from trc-Canada, 65usd/g for 5g. Other prices from sigma and mce are way more expensive.
If you are looking for cyclosporine for research, octagonchem will be your first choice. contact us now for a quote for comparison.
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