99% Emeramide Powder

MOQ	1 g
Port	Any port of China
Packaging	1g/bottle, 10g/bottle, 25g/bottle, 50g/bottle, 100g/bottle, 500g/bag, 1kg/bag
Lead Time	In stock

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Appearance

white powder

Product Details

What is Emeramide? (Irminix)

Cas number: 351994-94-0

Molecular Weight: 284.4g/mol

Molecular Formula: C12H16N2O2S2

Emeramide is a white to off-white solid synthesized in the lab, also known as BDTH2, NBMI or [N1, N3-Bis-(2-Mercaptoethyl) Isophthalamide] .

It is one of our recently developed novel active melocules. It is a brand-new lipid-soluble antioxidant and a novel heavy metal chelator (Mainly used for mercury poisoning). Its structure is specifically designed to bind mercury(II) in water.

Due to small demand, we are still not producing it commercially till today.

It is insoluble in water but easily soluble in fat or lipids. It is also soluble in DMSO(DMSO is the solvent for its 1HNMR testing).

Emeramide was previously used for treating mercury contaminated soil and water, but later it is also found to be able to detox animals with mercury poisoning.

It is the most well-known reagent so far used for precipitation of mercury from water. The precipiate of BDT-Hg or NBMI-Hg is so stable that it will suck and capture almost all mercury in water, even though mercury concentration level in aqueous solutions is very low.

What makes BDTH2 better is that BDTH2 will still be binding mercury even after it is oxidized into disulfide.

It will work in all sorts of water solutions, no matter what the PH is: acidic, basic, or neutral.

What Heavy Metals Can Emeramide Chelate?

Except the notorious mercury, BDTH2 is also proved to be effective on precipitating other divalent metals in water such as copper, lead, arsenic, selenium, cadmium, etc.

Scientific studies show that emeramide is able to chelate mercury, lead, cadmium, copper, manganese, zinc, iron across blood-brain barrier.

Mercury (Hg), especially from the groundwater, goal ore, wastewater of battery-recycling plants, coal tailings, and contaminated soil can be effectively chelated so the water can be cleaned.

What Are The Symptoms of Heavy Metal Poisoning?

There are two types of heavy metal poisoning, acute and chronic poisoning.

What we are talking about here is chronic poisoning by heavy metals. We can find heavy metals everywhere, in the water, air, foods, and toys, etc. If you live in a heavy metal polluted environment for a while, there are risks that you may get heavy metal poisoning.

Common symptoms of heavy metal poisoning include nausea, vomiting, shortness of breath, diarrhea, abdominal pain, tingling of your hands and feet, chills, and weakness. It is better to see a doctor right away when you have these symptoms when you have lived in such environments polluted by high-level heavy metals.

How Is Emeramide Produced In Lab?

The synthesis of NBMI can be done in one-step synthesis as shown on the left. Just make sure the reaction takes place at a low termerature.

We first dissolve 2-aminoethylthiol hydrochloride in chloroform and triethylamine and placed in an ice bath with stirring. Then we add the solution containing Isophthaloyl chloride dissolved in chloroform slowly. Then we stir the mixture flask in an ice bath for two hours.

NBMI will precipiate after we add about 100 mL of 0.1 mol L−1 HCl. Later we collect the and dry the powder to get what we need.

Dosages

It was designated as an orphan drug by the European Commission and USFDA since 2012.

For now, it is still under processing by the pharmaceutical company EmeraMed Limited with the trade name as Irminix. Currently, the drug developing company can offer a 14-day treatment x 300mg per day of Irminix®.

For more details, please check the web of EmeraMed Limited.

How Does Emeramide Work In Vivo?

Toxicity of mercury occurs at the intracellular level by binding of Hg2+ with thiol groups of relevant proteins. It has been proved in amimal models that mercury toxicity can be relieved by the use of BDTH2, which is able to cross the cell membrane and the blood brain barriers to chelate Hg2+.

Also in clinical trial tests performed by Emeramed Limited, BDTH2 is proved to be a safe, effective way to detox mercury without the issues and side effects of other chelating agents.

In-vivo research (300mg per day) shows that it captures mercury and other heavy metals, which helps create free radicals and thereby restores normal functions to the mitochondria and overall health.

There is no known toxicity shown by emeramide. It has been sold as a nutritional supplement under trade name of OSR-1 for many years.

The trade name of Irminix, has also been approved by the European Medicines Agency.