Epimedium Extract Icariin

Product Details

Epimedium Extract Icariin

Icariin is a flavonoid glycoside and the main active ingredient in Epimedium. It is typically standardized to 10-60% and is known for its ability to improve sexual function, increase bone density, and enhance cognitive function. The detection method for icariin is typically HPLC.

Botanical Source: Epimedium (commonly known as horny goat weed)

Extract Part: Whole plant, primarily leaves and stems

Extraction Type: Herbal extract

Extraction Method: Supercritical CO2 extraction

Extraction Solvent: Carbon dioxide

Detection Method: HPLC (High Performance Liquid Chromatography)

Grade: Pharmaceutical grade

Odor: Characteristic odor

Color: Yellow to brownish-yellow

Appearance: Powder or crystalline solid

CAS Number: 489-32-7

Molecular Formula: C33H40O15

Molecular Weight: 676.66 g/mol

Pharmacological Properties

1. Antioxidant Properties

Icariin has been shown to have potent antioxidant properties. It scavenges free radicals and reduces oxidative stress, protecting cells and tissues from damage. Icariin has been shown to increase the activity of antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), and decrease the levels of reactive oxygen species (ROS) in cells. The antioxidant properties of icariin make it a promising therapeutic agent for preventing and treating various diseases, including cardiovascular disease, neurodegenerative diseases, and cancer.

2. Anti-Inflammatory Properties

Icariin has been shown to have anti-inflammatory properties. It inhibits the production of pro-inflammatory cytokines, such as interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α), and reduces the activation of inflammatory pathways, such as nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinases (MAPKs). The anti-inflammatory properties of icariin make it a potential therapeutic agent for treating inflammatory diseases, such as rheumatoid arthritis, inflammatory bowel disease, and asthma.

3. Neuroprotective Properties

Icariin has been shown to have neuroprotective properties. It protects neurons from oxidative stress, apoptosis, and inflammation, and promotes neuronal survival and differentiation. Icariin has been shown to improve cognitive function in animal models of Alzheimer's disease and stroke. It also has potential as a therapeutic agent for treating other neurological disorders, such as Parkinson's disease and multiple sclerosis.

4. Anti-Cancer Properties

Icariin has been shown to have anti-cancer properties. It inhibits the proliferation, migration, and invasion of cancer cells and induces apoptosis. Icariin has been shown to have anticancer effects in various types of cancer, including breast cancer, prostate cancer, lung cancer, and liver cancer. It also enhances the efficacy of chemotherapy and radiation therapy, making it a promising adjuvant therapy for cancer treatment.

5. Osteoprotective Properties

Icariin has been shown to have osteoprotective properties. It promotes osteoblast differentiation and mineralization and inhibits osteoclast differentiation and activity, leading to increased bone mass and strength. Icariin has been shown to have beneficial effects on bone health in animal models of osteoporosis and bone defects. It also has potential as a therapeutic agent for preventing and treating bone disorders, such as osteoporosis and bone fractures.

6. Anti-Aging Properties

Icariin has been shown to have anti-aging properties. It activates the AMP-activated protein kinase (AMPK) pathway, which regulates cellular energy metabolism and promotes longevity. Icariin has been shown to improve mitochondrial function and reduce oxidative stress in aging cells. It also enhances the expression of genes associated with longevity and improves the lifespan of various organisms, such as worms and flies.

Who We Are

Fufeng Sinuote Biotechnology Co., Ltd. is a leading plant extract manufacturer in China, specializing in the research, development, production, and promotion of plant extracts. Our company has all the necessary qualifications such as SC, export license, commodity inspection qualification, and more.

Our Expertise

We boast over ten years of experience in the plant cultivation industry, with our own plant planting base covering an area of more than 1000000 square meters in Gansu & Ningxia Province, China. This enables us to maintain better control over plant quality, resulting in better-quality extract powder.

Our Products

We manufacture over 600 types of plant extracts, including ginseng, echinacea, and more. Our extracts have been widely used in the food, supplement, and cosmetics industries. With strict quality control and efficient production, we guarantee high-quality extracts for your business.

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Apart from our extensive product range and superior quality, we have a professional export sales team that can assist with all inquiries, offer flexible payment terms, and timely delivery. We strive to build long-term business relationships with our clients, and our positive feedback from customers worldwide proves our commitment.