China Factory Supplier CAS 73590-58-6 Omeprazole

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Omeprazole is a proton pump inhibitor used for the treatment of peptic ulcer and gastroesophageal reflux disease (GERD) and other diseases. It can specifically act on the site of the proton pump in the gastric wall cells, and is transformed into the active form of sulfamide, and then irreversely binds to the sulfol group of the proton pump through disulfide bonds. The formation of sulfoamide and proton pump (H+-K+ -ATPASE) complex, thereby inhibiting the activity of the enzyme, so that H+ in the parietal cells can not be transported to the stomach, blocking the final step of gastric acid secretion Chemicalbook, can greatly reduce the amount of gastric acid in gastric juice. Therefore, this product has a strong and durable inhibitory effect on gastric acid secretion caused by various causes (e.g., basal gastric acid secretion and gastric acid secretion caused by histamine, pentagastrin and vagus nerve stimulation, including dibutyl cyclic adenylate induced gastric acid secretion which cannot be inhibited by H2 receptor blockers). This is related to the irreversibility of the inhibition of proton pump, and only after the formation of a new proton pump, the acid-secreting effect can be restored.

1.Proton pump inhibitors, or parietal H+-K+ -ATPASE inhibitors. It has strong and lasting inhibitory effect on the secretion of basic gastric acid and gastric acid caused by food and pentapeptide gastrin. The effect was rapid and reversible, and there were no mental side effects of H2 induced by Chemicalbook antagonist. It is used for gastric and duodenal ulcers, reflux or erosive esophagitis, zoe-Erzer's syndrome, etc. It is also effective for gastric and duodenal ulcers that do not respond to H2 receptor antagonists.

2.Omeprazole is a proton pump inhibitor that has strong and long-term inhibition of gastric acid secretion in animals and humans. Clinically, it has been used for the treatment of peptic ulcer Chemicalbook, reflux esophagitis, Zollinger-Ellison syndrome and eradication of Helicobacter pylori (HP) with satisfactory efficacy.

3.Omeprazole is a proton pump inhibitor that has strong and long-term inhibition of gastric acid secretion in animals and humans. Clinically, it has been used for the treatment of peptic ulcer, reflux esophagitis, chemical bookZollinger-Ellison syndrome and eradication of Helicobacter pylori (HP) with satisfactory efficacy. Applicable to peptic ulcer, reflux esophagitis and so on.