√ Target List was recommended by AZ, GSK, Novartis and Pfizer in 2012
√ ICE’s Functional assay correlated better to the physiological and pharmacological function
√ Both agonist and antagonist modes are available
√ Flexible in target selection and assay formats:
o FLIPR/cAMP/IP1/Reporter gene assay
o Biochemical assay/Electrophysiological assay
o GPCR x 24
o Ion channel x 8
o Enzyme x 10/
o Monoamine transporter x 3
o Nuclear receptor x 2
√ Fast turnaround time, 3-4 weeks
√ Cost effective
√ Include reference compound in each run
√ 100+ target panel is under validation
√ Currently we have 70 targets are ready
√ Provide both CN and EN version reports
√ Enable IND filing